Presentation Abstract: New Aggressive Approaches To Disconnecting The Inflammation-Depression Connection. World Congress On Anti-Aging Medicine And Regenerative Biomedical Technologies Expo (A4MC) Shanghai, China October 18-20, 2012

Depression ICD-9 296.3

Title: New Aggressive Approaches To Disconnecting The Inflammation-Depression Connection.
To be presented at: The World Congress on Anti-Aging Medicine and Regenerative Biomedical Technologies Expo
Date: Oct 18-20th, 2012
Address: Shanghai World Expo Exhibition & Convention Center
1099 Guo Zhan Road, Shanghai, China, 200126 
By Dr James Stoxen DC
Depression is a mood disorder that affects serotonin levels in the brain. Because of its physiological cause, many people believe that clinical depression must be cured through chemical intervention. Drug Free Therapy for signs of depression might include A healthy diet which plays an important part in healthy brain depression symptoms. Eating vitamin-rich foods balance out chemicals in the brain and provides a natural intervention for depression for some who experience severe depression syndromes. Avoiding complex sugars and too many carbohydrates, which lead to mood swings, helps stabilize emotions. Adding exercise cannot go overlooked as an important aspect of a drug-free depression treatment. Talk therapy, Cognitive behavioral therapy and interpersonal therapy are also very effective in overcoming chronic depression. Drugless depression treatments vary from person to person. However, herbal supplements and intervention have helped some patients. Consulting with a knowledgeable pharmacist or herbal treatment specialist can help you make the right choice for your specific treatment plan.

DR. STOXEN’S LECTURE STARTS AT 15:58 AND GOES THROUGH 16:12 ON THE VIDEO PLAYER ABOVE
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Presentation Abstract:
New Aggressive Approaches to Disconnecting the Inflammation-Depression Connection
Depression represents a major public health problem it is estimated that up to 16 – 20% of the population has had depression at any one time and that 5 to 7% of the population is assumed to suffer from major depression. Studies have also shown that there is a correlation between chronic depression and the development of Alzheimer’s, Parkinson’ and dementia in later life.
There is substantial literature linking inflammation with the risk for depression. The purpose of my presentation is to list the inflammatory mediators and their link to depression. Patients with inflammatory disorders such as MS, cardiovascular disorders, rheumatoid arthritis, osteoarthritis
Increase inflammatory cytokine expression and the development of concurrent psychiatric symptoms were initially observed after administration of cytokine therapy to patients afflicted with cancer hepatitis and MS. It has been found that patients with depression have high levels of inflammatory biomarkers. This suggests that inflammation can be a mediator for depression.
The purpose of this presentation is to review these studies and determine their potential to lead to interventions which may reduce the risks for inflammatory diseases of aging such as osteoarthritis cardiovascular disease and his symptoms related to varying degrees of depression.
Depression it is obviously a stress sensitive disorder however the actual causal mechanism for their relationship is unknown. Research team led by Carnegie melon University’s Sheldon: has found that chronic psychological stresses associated with the bodies losing its ability to regulate the inflammatory response which can promote the development and progression of the disease called depression. So while inflammation can cause or be linked to depression, and the stress and depression can also be linked back to inflammation.
Aging is also associated with increased likelihood of chronic pain and inflammatory conditions. A part despite improving knowledge is of underlying mechanisms of chronic pain many patients who have chronic pain receive inadequate care both short-term and long-term. We are going to discuss some novel ways to reduce chronic pain, chronic inflammation and disability dust reducing overall inflammation and possibly reducing the risk of the development and exacerbation of chronic depression.
We will also discuss the treatments, which can and may reduce depression. Currently antidepressants only produced remission and 30% of patients. The part of the problem is that the pathophysiology of depression has not been well understood and treatments are based on empirical data and not on the mechanisms or causes of action. Many research studies suggest that addressing pro-inflammatory cytokine production represents a possible strategy to treat depression besides the use of psychotropic drugs.
This will include the relationship between dietary influences and the risk of depression, and fatty acid supplementation for the fresh and add the adiposity risk factors for childhood and adult onset depression. I will also discuss the role of inactivity in inflammation and end depression as well as the effects of exercise and the increase and decrease of inflammation associated with exercise.
I will discuss natural ways to decrease levels of systemic inflammation both from a treatment and preventive approach to use with or without psychotropic drugs.